Neonatal tetanus treated with high dosage diazepam.

Neonatal tetanus treated with high dosage diazepam.

The combination of continuous intravenous infusion of diazepam (20--40 mg/kg per day) and intragastric phenobarbitone (10--15 mg/kg per day in 4 divided doses) was used to treat 19 cases of neonatal tetanus. Mortality was 2/19 (11%). This regimen was considered to have reduced the mortality and the need for artificial ventilation. The main side effects encountered were severe drowsiness, coma, ...

A Case of Tetanus, Treated with Tetanus Antitoxine: Recovery

The patient was a male, aged 25, well developed and well nourished. The illness began six days before admission into the J. J. Hospital, with severe headache, and attacks of pain and rigidity of the muscles of the neck and jaw. On the following day the rigidity increased in the muscles at the back ot the neck, and appeared in the anterior abdominal muscles. He was then compelled to take to his ...

Eliminating Neonatal Tetanus

Neonatal tetanus associated with skin infection.

A 1-week-old infant was brought to a regional hospital with a history of recurrent seizures following lower abdominal septic skin infection. She was found to have neonatal tetanus, and a spatula test was positive. The tetanus infection was associated with a superficial skin infection, common in neonates. Treatment included sedatives (diazepam, chlorpromazine, phenobarbitone and morphine), muscl...

Maternal and neonatal tetanus.

Maternal and neonatal tetanus are important causes of maternal and neonatal mortality, claiming about 180 000 lives worldwide every year, almost exclusively in developing countries. Although easily prevented by maternal immunisation with tetanus toxoid vaccine, and aseptic obstetric and postnatal umbilical-cord care practices, maternal and neonatal tetanus persist as public-health problems in 4...